The change in load capacity between the control specimens and other groups are found within the acceptable single laboratory coefficient of variation precision 1 s % of 14.4%.
Thus, Lin coefficient combines measures of precision and accuracy.
The final model is established on the basis of additional statistical analysis using other statistical criteria (coefficient of variation, adequate precision, Mallow's Cp statistic), the convenient results obtained, ensuring a satisfactory quadratic regression model, including all main parameters and their quadratic terms.
In addition, per anatomical region, the coefficient of variation (COV, precision) and bias (accuracy) was calculated.
The coefficient of variation (CV; precision) and percent bias (accuracy) for the multiple runs during the period of analysis for five quality control samples of 2.00, 5.00, 400, 2,000, and 4,000 ng/ml were 9.8 and 2.0, 4.9 and −2.4, 6.1 and −5.3, and 6.8 and 2.0, respectively.
The planned sample size will have 85% power to detect reliability coefficients within an acceptable level of precision (estimated coefficient > 0.4 when the true value is 0.6).
A sample size of 15 patients per arm was considered sufficient to determine the dose needed to achieve the target Cmin with an acceptable degree of precision (coefficient of variation <15%).
Because the summary measures we examined likely would be used in lieu of the gold standard (i.e. this was an inter-method comparison), and because contaminant levels were non-normally distributed, we estimated Spearman's correlation coefficient as a measure of precision [ 16].
The intra-assay precision coefficient of variation (CV) is 3.86% and the inter-assay precision CV 8.47%.
