Sentence examples for codon reassignment from inspiring English sources

Here we summarize some of those advances, and provide detailed protocols for codon reassignment.

Codon reassignment is leading to important advances in protein engineering and bioorganic chemistry.

In this case, codon misreading by mutant or wild type tRNAs works as a trigger for codon reassignment [10] [13].

Global residue-specific substitutions are possible using unnatural amino acid mutagenesis via a codon reassignment strategy [6], albeit with heterogeneous products resulting (vide infra).

Furthermore, our findings are potentially significant for future synthetic biology applications because they open up the possibility for re-engineering of variants of natural proteins into which unique chemical functionalities can then be introduced, for instance using codon reassignment and unnatural amino acid mutagenesis [6], [2].

This codon reassignment has been proposed to have occurred ~170 million years ago [ 45].

Metagenomic analysis reveals extensive and diverse stop codon reassignments among environmental microbes and phages.

In fact, we treat both codon assignments and codon reassignments in code-message coevolution theory.

This explains why the majority of codon reassignments occur in the small genomes of mitochondria.

Considering the robustness of our phylogeny, the profound genetic changes that coincide with codon reassignments and the scarcity of codon reassignments, we conclude that a stepwise acquisition model is the most likely hypothesis.

Most codon reassignments have been traced to changes in tRNAs, either by single nucleotide substitution, base modification, or RNA editing.