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Visual behaviour was coded using a 'data reduction' approach and coding taxonomy of visual behaviour similar to that used in the 100-car study [2].
Additional file 2: Coding taxonomy for predictor variables.
The final stage of analysis involved the development of a complaint coding taxonomy.
In this study the ICF coding taxonomy was employed and individual DASH items were assigned one or more ICF code.
To overcome some of the issues highlighted above, we have developed a three-level complaint coding taxonomy (figure 4).
99 In developing and implementing the coding taxonomy described in figure 4, three stages may be undertaken.
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There are also idiosyncrasies in the Read Code taxonomy, in particular the fact that codes for a lack of existence of a symptom can occur as leaf nodes describing that symptom.
Using the ICD-10-CM code taxonomy to identify diagnoses and procedures, we excluded the diagnosis type with M (main diagnosis) or a 2 (post admit co-morbidity) because these conditions were the cause or consequence of the hospital admission, and not a pre-existing comorbidity.
Future work will include construction of a thorough non-coding taxonomy, the implementation of all POEM categories in a genefinder and the addition of multiple dimensions to POEM.
In order to limit the search space of compounds, such database approaches would benefit if information was given in which organisms (coded as taxonomy source) and in which organs or cell types these metabolites were known to exist.
However, within these codes, the taxonomy defines specific BCTs used to achieve these targets (see Table S1 for examples).
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