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Coding of treatments, prescriptions and referrals by GPs in primary care has also received some attention.
After coding of treatments, a qualitative analysis was performed through ultraviolet (UV) absorption spectra on samples of homeopathic treatments, saline and indomethacin.
While several studies have measured the validity of diagnostic coding in the DNPR, 8– 10 the validity of most coding of treatments, including bisphosphonate therapy, has not been evaluated.
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It is also recognised that the coding of treatment procedures were of high quality and well recorded with the Northern and Yorkshire Cancer Registry and Information Service United Kingdom Association of Cancer Registriess, 2009).
In the absence of standardized collection and coding of treatment data by a cancer registry or other data source, administrative data are the most available data sources for basic information related to receipt of treatment, particularly hospital-based treatment [ 8, 9].
Large-scale observational studies based on existing medical databases may have an important role in studies of long-term effects of different treatments in prostate cancer patients if the coding of the treatment is valid.
Using this coding of the treatment group indicator, we assume equal variability in the log hazard rate across trials for both treatment groups.
The finding of an overall high PPV for the coding of bisphosphonate treatment is on a par with or better than validity reported for other procedures and for diagnostic coding.
After completion of these analyses, the patient treatment responses were matched to the miR response data and are shown with a color code indicative of treatment responses (see Fig. 1b).
17 Severe psoriasis was defined by the presence of a prescription code for treatments consistent with severe psoriasis on or after the diagnosis of psoriasis (such as phototherapy including ultraviolet B or psoralen and ultraviolet A (PUVA), methotrexate, azathioprine, cyclosporine, oral retinoids, hydroxyurea, mycophenolate mofetil, etanercept, adalimumab, infliximab, and ustekinumab).
To our knowledge, no other study has been published on the coding of GnRH agonist treatment or orchiectomies in the DNPR or any other registries.
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