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In this study, a fluorescent aptamer-based sensor (aptasensor) was designed for sensitive and selective detection of cocaine, based on hairpin structure of complementary strand of aptamer (CS), target-induced release of aptamer (Apt) from CS and two kinds of nanoparticles, including silica nanoparticles (SNPs) coated with streptavidin and gold nanoparticles (AuNPs).
An integrated platform for a very sensitive detection of cocaine based on a refractometric biosensor is demonstrated.
We have developed an amplified detection method for cocaine based on a strand-displacement polymerization reaction using aptamer recognition.
In this study, an electrochemical aptasensor was designed for sensitive and selective detection of cocaine, based on single-walled carbon nanotubes (SWNTs), gold electrode and complimentary strand of aptamer (CS).
More importantly, a significant prenatal treatment condition (prenatal cocaine, control) by sex interaction in nestin+ expression was confirmed, indicating different effects of cocaine based on sex of the animal.
In this work, an electrochemical aptasensor was designed for sensitive and selective detection of cocaine, based on complimentary strands of aptamer (CSs), H-shape structure of Aptamer (Apt -CSs conjugApt -CSsgold eleconjugate
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In 2000, more than twenty innocent African-American men in Hearne, Texas, were arrested on cocaine charges, based on the false accusations of an informant seeking to escape a burglary charge; the incident, and a number of others like it, prompted calls for national legislation to regulate informant use.
More than 23 years ago, at the height of public hysteria over the effects of crack cocaine and based on myths that have since been entirely debunked, Congress passed, and President Reagan signed into law, legislation that established the infamous 100 to 1 disparity.
The rationale for choosing the above mentioned range of cocaine was based on the following reports.
The criteria used to choose a drug to be combined with crack cocaine were based on the experience of other users, experimentation, and the individual evaluation of the effects of the combination tested.
The therapy group will receive a 6-week self-help therapy to reduce cocaine consumption based on methods of Cognitive Behavioural Therapy, principles of Motivational Interviewing and self-control practices.
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