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Film coating uniformity is an important quality attribute of pharmaceutical tablets.
Another trend has been the requirement for an increase in the coating uniformity.
It was successfully used to identify critical process parameters regarding intra-tablet coating uniformity.
A low spray rate and a high pan speed improved the coating uniformity at both scales.
The second algorithm predicts the asymptotic limit of intra-tablet coating uniformity.
A higher pressure and use of power modulation can improve the coating uniformity in fissures.
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Under the quality-by-design framework, particle recirculation within the partition column is one of the main variability sources affecting particle coating and coat uniformity.
The coating film uniformity of a Newtonian fluid on a spinning disc is analyzed theoretically.
The factor for a quantitative reassessment of the criticality and risk priority is the coefficient of variation, which represents the coating mass uniformity.
Process parameter screening studies are statistically planned under consideration of impacts on a potentially critical quality attribute, i.e., coating mass uniformity.
While the applied current density did not appear to affect the Mn3O4 particle incorporation, it had a strong influence on coating thickness uniformity.
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