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DOI: http://dx.doi.org/10.7554/eLife.05553.015 The haptoglobin-haemoglobin receptor operates in the context of the VSG layer, a dense coat of surface protein that covers the trypansosome surface.
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The coating of surface modified agents over the oleic acid-capped iron oxide nanoparticles was confirmed by Fourier Transform Infra Red spectroscopy (FTIR, Varian 3100).
Both of these strategies require a densely packed cell surface coat of variant surface glycoprotein (VSG) that acts as a barrier, preventing access of host immunoglobulins to the plasma membrane (Schwede and Carrington, 2010).
Laser cladding is a welding process used for coating of surfaces.
It is likely that one of the most promising areas for improvement lies in the modification or coating of surfaces to reduce fouling and enhance cleaning.
Although more closely reflecting the natural situation, fibronectin coating of surfaces did not significantly influence the biofilm forming ability of the tested mono-species as compared to uncoated supports.
It also avoids the need for vacuum conditions or the coating of surfaces with layers of metal that may interact with samples and cover their fine natural structure.
With native CPPs, stable coating of surfaces is not possible due to their good water solubility, but protein modification, coupling to or mixing with other proteins could enable this.
Key to survival is a dense protective coat of Variant Surface Glycoprotein (VSG) [ 16], which is essential for the bloodstream form trypanosome even in vitro [ 17].
Expect a new version of the maxi coat to surface for winter.
Two different procedures were used for coating of PET surface with silver nanoparticles.
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