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Standard coagulation variables were similar between the 2 groups.
To evaluate and compare coagulation variables following the administration of oxypolygelatin and dextran 70 to clinically healthy dogs.
Patients treated with bivalirudin achieved significantly better coagulation variables.
Further, histopathology, haemodynamics and several coagulation variables were also assessed.
Dabigatran levels were comparable between groups (571 ± 174 ng/ml) and resulted in altered coagulation variables.
Blood samples for measurements of coagulation variables were taken daily for the following 3 days.
Similar(35)
The vital signs, resuscitation endpoints, organ dysfunction scores, and coagulation-related variables were similar in these groups at baseline [ 25].
A single dose (1 mg/kg) was applied via intravenous infusion over a period of 30 minutes Coagulation-related variables, blood count and clinical parameters were taken before the treatment and until 48 h after treatment.
According to a Kolmogorov-Smirnov analysis, the coagulation and fibrinolysis variables showed a skewed distribution.
Secondarily, we analysed the effect of TPE on respiratory, coagulation and biochemical variables.
The remaining variables (coagulation parameters) did not show significant differences (data not shown).
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