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The coagulation panel was within normal limits except for elevated D-dimer levels at 19.6 μg/ml.
The coagulation panel of the prothrombin time international normalized ratio was abnormal at 2.78, and her fibrinogen level had decreased to 34 mg/dl.
Citrated blood samples were collected daily during hospitalisation and diagnosis of DIC was based on the expert evaluation of an extended coagulation panel.
A coagulation panel was unremarkable.
Further laboratory tests including ANA, anti-GBM IgG, complements, viral hepatitis screen, ESR, CRP, VWF, ANCA, sputum AFB ×3 and coagulation panel, were all within normal limits.
Initial laboratory testing included a complete blood count with differential, chemistry panel, coagulation panel, urinalysis, and computerized tomography (CT) scans of the abdomen and pelvis.
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All coagulation panels were also found to be within normal limits.
Coagulation panels were carried out with the IL ACL 3000 Coagulation Analyzer (Beckman Coulter, Brea, CA, USA).
ML and NPJ are members of an expert panel dealing with coagulation and coagulation disorders in critically ill patients.
The initial workup in the ED included a complete blood count (CBC), basic metabolic panel (BMP), coagulation studies [prothrombin time (PT), partial thromboplastin time (PTT), international normalization ratio (INR ], and a urine toxicology screen.
Figure 1G demonstrates that Cyr61 displays no inhibitory properties toward a panel of coagulation factors including thrombin, Factor Xa, Factor XIIa, and kallikrein.
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