Before biopsy, all coagulation indicators were within the normal range and blood pressure levels of patients were maintained below 140/90 mmHg.
Demographic and disease data of patients included age, gender, chief complaint for admission, vital signs, routine blood test results, liver and kidney functions, coagulation indicators, Acute Physiologic Assessment and Chronic Health Evaluation (APACHE) II scores, and Sequential Organ Failure Assessment (SOFA) scores.
CI (normal range -3 to 3 mm) is an overall indicator of coagulation and indicates normal, hypo- or hypercoagulable state.
A third study looked at platelet count, a sensitive marker of intravascular coagulation and useful indicator of tumour-induced clotting activation.
Abnormal laboratory values of coagulation disorder may be indicators to predict intraoperative circulatory failure, as well as physical or radiographic finding, if more evidence is established.
Preliminary results from our UFP-controlled human exposure study showed a 10 25% increase in indicators of coagulation: prothrombin fragment F1+2 and D-dimers (unpublished observation).
We identified 19 soluble biomarkers (15 prospectively and four post hoc) that were indicators of coagulation activation, anticoagulation, fibrinolysis, endothelial injury, and inflammation in sepsis, and measured these biomarker concentrations in patients entering PROWESS at baseline.
All specimens for blood indicators and coagulation measurements were collected by venipuncture into 5 mL drying VACUETTE vacutainers (Greiner Bio-One GmbH, Kremsmunster, Austria) and 5 mL Becton Dickinson vacutainers containing 0.5 mL 0.109 M sodium citrate (Becton Dickinson, Franklin Lakes, NJ, USA) in the morning after a 12-hour fast.
According to OECD 236, the following parameters were used as indicator of mortality: coagulation of fertilized eggs, lack of somite formation, lack of detachment of the tail bud from the yolk sac, and lack of heartbeat.
To determine whether sEPCR released from leukemic cells might be an indicator of the coagulation status in patients, we evaluated sEPCR in plasma and in bone marrow supernatants of patients with malignant hemato-logical diseases.
Recently, the use of rhAPC has been shown to be of benefit with a reduction in mortality and an improvement in indicators of inflammation and coagulation.
