We identified 15 CNV in the cohort 68 ASD patients, giving CNV detection rate of 22.1%%.
This was consistent when CNV in subtelomeric genes or non-subtelomeric genes were considered separately (non-CNV vs. CNV in sub-telomeric regions, p = 0.10; non-CNV vs. CNV in non-subtelomeric regions p = 0.98, Kolmogorov-Smirnov test).
On day 14 post laser induction (7 days post treatment) the sizes of CNV in all mice groups were measured, and also compared to original size of the CNV in mice 7 days post laser induction (untreated).
All patients with clinically significant CNV in the adult group were male.
Clinical examination and investigations show the development of CNV in the left eye.
FA and OCT confirmed active inflammation (choroiditis without CNV) in five patients.
We identified 11.8 % patients with clinically significant CNV in our ASD cohort by array CGH.
Peripapillary CNV in the context of intermediate uveitis appears to respond well to VEGF-inhibitor therapy.
Most cases of CNV in uveitis occur in posterior uveitis or panuveitis.
The presence of CNV in childhood asthma has only been recently discovered.
We report an optimized method for the determination of copy number variation (CNV) in GST genes.
