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Finally, when siMyc-treated BJEL cells were additionally incubated with CMS, we observed not only an expected higher initial amount of FLIP, but also a failure of CMS to downregulate FLIPL levels under conditions of MYC depletion (Fig. 3F).
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However, when we supplemented recombinant RANTES with CSML0-CM, we observed S100A4 secretion from fibroblasts in a dose dependent manner, suggesting that a certain factor(s) in CSML0-CM cooperatively act with RANTES (Fig. 1B).
Specifically, in the subgroups G4 and G5 at distances 45 and 74 cM we observed larger LD peaks.
Whereas survivin expression did not change in the presence of CA-MSC CM, we observed a decrease in the expression of cIAP1 and Livin (Supplementary Figure 6).
Using their CM, we observed a decline in the formation of TRAcP+ polykaryons, together with a lower transcription of major OC factors and decreased bone resorbing ability.
Similarly, at a distance of ~8 cM we observed a larger LD in both types (r2 0.247 for romaine, and 0.345 for crisphead) than in the whole set that combined multiple subpopulations.
In 87% of patients with FV in MCA > 185 cm/s we observed focal ischemic brain lesions verified on CT scan.
This value of Papp was much less than the value of Papp (4.47 × 10 6 cm/s) we observed in this study, but the apical concentration was also 100-fold less.
In the treated CM group we observed a significant reduction in headache and migraine days, abortive treatment intake and headache-related disability.
However, in experiments with a CO2 slurry mass (a mixture of dry ice and liquid CO2) of 8 cm size we observed that the released material could keep its shape and sink even further until the covering ice layer melted.
6 Following a similar protocol of infection and Cm treatment, we observed significant colocalization of LC3 with the ActAΔ L. monocytogenes, consistent with autophagy of bacteria (Fig. 3D).
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