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The expression of orf220 without mitochondrial-targeting peptides did not result in a CMS phenotype in Arabidopsis (data not shown).
We conducted extensive sequence comparison between Ks3 and Km3 mtDNAs to search for functional alterations of genes that were responsible for the CMS phenotype in plants.
Since ribosomal proteins are responsible for protein expression, these differences may be important to our understanding of CMS phenotype in plants.
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Future approaches generating ET-specific T cells against EZH2 and/or CHM1 with a central memory (CM) phenotype (Berger et al, 2008) in addition may yield improved anti-tumour efficacy.
They displayed a gradual shift from a CD44hiCD62Llo (EM) phenotype to a CD44hiCD62Lhi (CM) phenotype and increased levels of IL-2 production, in agreement with previously published results [31], [32].
Does the hiPSC-CM phenotype truly reflect the phenotype of the native myocytes in the patient, or does it reflect the effect of the gene mutation on cardiac differentiation and ex vivo culturing?
In contrast, the proportions of central-memory (CM -phenotype CM -phenotypecellsA−) were inCCR7+ed in patient groups II and III werehad been treated topincreasedth iniquimod (Fig. 2E).
In concert with the enhanced invasive ability of E-A549 cells after the cultivation with M-A549-CM, the secondary EMT phenotype in E-A549 cells was also induced after the culture with M-A549-CM.
In contrast, our data show that increased percentages of CM-phenotype cells (CD45RA−CCR7+) with enhanced expression of CD127 were induced by the addition of Imiquimod.
Top numbers show the genetic distance between the markers and the Rosetteless phenotype in centimorgans (cM).
Moretti et al were the first to show that iPSC-CMs can recapitulate the disease phenotype in humans.
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