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Testing BL/6J and D2Ola mice after long-term CMS experience revealed that BL/6J mice remained unaffected by CMS, whereas D2Ola mice of the CMS group showed a decrease in anxiety-related behaviour.
HTML and CMS experience is a plus.
Second, a different batch of BL/6J mice was investigated after 2 weeks of CMS experience when the decrease in saccharin intake became apparent.
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The CMs experienced that they sometimes had pushed the participant in the right direction, had convinced or coached the participant.
Another barrier was that the CMs experienced that the participants did not have any major problems that they could solve.
The CMs experienced feelings of guilt and stated that they were worried about what would happen with the participant when their visits ceased.
Individuals with CM experience substantially greater headache-related disability [4, 10 12] than individuals with episodic migraine (EM).
Patients with chronic migraine (CM) experience substantially impaired daily functioning and reduced quality of life, with daily or near-daily headache attacks.
Compared with people with episodic migraine (EM; <15 headache days per month), those with CM experience greater headache intensity, increased pain severity and disability, [2] higher rates of comorbid medical conditions, [2, 4] reduced health-related quality of life, [2] greater economic burden, [6] and reduced productivity.
A murine-based model of CM that better emulates the human CM experience is needed, and it must include a neurobehavioral score that is rapidly deployed.
Survivors of CM experience developmental and behavioral impairments [ 1, 2].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com