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In all, 2391 eligible patients were randomised and with a median 7.4-year follow-up, E-CMF confirmed a significant benefit over CMF in both relapse-free survival (RFS) (78% vs 71% 5 years RFS, respectively, hazard ratio (HR)=0.75 (95% CI: 0.65 0.86), P<0.0001) and overall survival (OS) (84% vs 78% 5 years OS, respectively, HR=0.76 (95% CI: 0.65 0.89), P=0.0007).
A feedback model between the stress perceived by a cell and orientation of the CMFs, which assumes an alignment of the CMF in the direction of maximal stress results in a very minor deviation of the stress pattern from the stress orientation obtained in the case of an isotropic material.
Similarly, in a survey in premenopausal women with node-negative breast cancer treated with or without adjuvant CMF, there were no long-term effects of CMF in general and breast cancer-specific QL domains (Joly et al, 2000).
The sequential doxorubicin → CMF (CMF=cyclophosphamide, methotrexate, fluorouracil) regimen has never been compared to CMF in a randomised trial.
Between 1984 and 1989, 1048 node-positive patients were treated with CMF in two separate trials conducted by the German Breast Cancer Study Group (GBSG).
Moreover, the Ni-CMF material is found to show a high electrical conductivity compared to pure CMF in HDCFC operating conditions.
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Catastrophic mass flows (CMFs) in the glacial environment are an important geomorphic process that may pose significant hazard to communities and infrastructure in glacierized mountains.
However, in many situations, there are no CMFs in the literature to predict the safety impact of changing particular road features.
These results suggest that the microgravity environment itself at best only slightly affected either cell wall biopolymer synthesis or the deposition of CMFs, in contrast to previous assertions.
The interlaminar shear strength (ILSS) and tribological properties of HSGF/phenolic laminates modified by CNFs and CMFs in water environment were comparatively investigated.
Broadly, CMFs in the glacial environment are characterized by a sudden onset, high mean velocity (≥5 m/s), high mobility (i.e., long runout in relation to volume), and generally involve a mixture of earth materials, water, snow, and ice.
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