Sentence examples for clusters were enriched from inspiring English sources
Furthermore, through motif enrichment they found that genes in these clusters were enriched in AP1, JUN, CREB, ATF, EGR, and PPARA binding sites, indicating that components of our core response module may be regulated by the Fos/Jun AP1 complex, and the Egr1 and 2 transcription factors that are in the module as well.
Pathway analysis further confirmed that these clusters were enriched for the same biological processes, notably the translational activities and the acetylation pathway (Fig. 3c, d and Supplementary Data 1 & 2).
Focal adhesion (left panel) gene clusters were enriched at day 5 and RHO GTPase (middle panel) and actin cytoskeleton-related gene clusters (right panel) at day 8 upon HSF2 silencing.
Both the embryonic and post-embryonic clusters were enriched with members of distinct pathways and GO categories (Figure S5).
In contrast, the most downregulated clusters were enriched with genes related to lipid, nucleotide, and amino acid metabolism.
Two, AChR clusters were enriched in cortactin phosphorylated on its src-target tyrosine residues, whose phosphorylation enhances Arp2/3-mediated actin polymerization [33].
Second, we wanted to see whether our predicted gene target clusters are enriched in the corresponding binding sites for the transcription factors in their upstream region.
For those TRNMs for which two transcription factors are involved, we also find these downstream gene clusters are enriched in both the binding site sequence motifs.
In contrast, Saccharomycotina specific protein clusters are enriched in transcription and mitochondrion related functions.
As expected, out of 102 clusters identified, several clusters are enriched for rapidly accelerated or decelerated proteins within each cluster.
