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The C-terminus of Msn2p contains four arginine- and lysine-rich clusters that function as a classical NLS [ 128].
ATF4 occupies sites near all of the genes observed in the HD-primed clusters that function in amino acid transport and metabolism and tRNA aminoacylation (Supplementary file 1).
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The polycomb group proteins are well-studied epigenetic regulators of the fly homeotic gene cluster that function as silencers and help maintain the transcriptional history of target genes over many cell generations [18].
With this in mind, we are developing molecular cluster compounds that function in the proton-coupled reduction of small molecules, such as CO2 or N2, and facilitate the manipulation of hydrogen atoms of organic molecules for selective bond (de construction.
In general, small and medium sized clusters tend to contained proteins of known function in contrast to large clusters that contained proteins that function in distinct but coordinate processes.
The subsystems are annotated across genomes and are based on biochemical pathways, fragments of pathways, and clusters of genes that function together, or any group of genes considered to be related.
The upregulated clusters comprised transcripts that function in protein translation, cytoskeleton organization, cell cell signaling, and ion channel activity.
Moreover, this result demonstrates that choice of reference genomes selection can also be used to identify Co-Conserved clusters of proteins that function in distinct pathways (regulators, cyclic-di-GMP metabolism, etc).
An alternative to replicating data across a WAN consists of having a local cluster subsystem that functions as a backup.
There are also some rumbustious sex scenes (treated with the same tolerant, wholesome curiosity that Murakami devotes to the stir-frying of food), as well as a cluster of details that function as generous and reassuring fan-service, such as a young woman with a beautiful ear, or the obligatory apparitions of cats and crows.
Thus, unlike the mouse, which contains a single HES6 gene, encoding a protein that works mainly by interfering with the anti-neurogenic activity of other HES proteins, the chick embryo contains two clustered HES6 genes that function through different but complementary mechanisms to regulate neuronal differentiation.
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