PCN061 does not harbor these two gene clusters that are involved in aromatic compound degradation.
There are two non-ribosomal peptide synthetase (NRPS) gene clusters that are involved in the generation of ferrichrome and ferrichrome A, while the terpenes gene cluster is composed of three unknown function genes and seven biosynthesis related genes.
For example, X. albilineans has acquired a T3SS of the SPI-1 family that is mainly found in free-living animal pathogens and four NRPS gene clusters that are involved in the biosynthesis of albicidin and probably other unknown small molecules.
For instance, Li et al. [ 66] found 33 EST clusters that were involved in immune and defense functions in Meretrix meretrix.
In the G. raimondii genome, the RGA genes in the Rgrcs were also induced, which most likely indicated that the RGA genes formed clusters that were involved in Verticillium wilt resistance (Fig. 6), similar to the resistance clusters in many other plants [ 75– 75].
In addition, expression increased for several genes in this cluster that are involved in the regulation of NK cell functional activities, such as KIRs (Kir2DL4, Kir3DL2, Kir2DS2, Kir2DL2 and Kir2DS1), granzyme-B and Ksp37 for cytotoxicity, and CARD11 (CARMA1) for the regulation of cytokine/chemokine production (Fig. 2B) (Table S2).
Genes other than the nif gene cluster that are involved in N2 fixation and are homologues of Bradyrhizobium japonicum USDA110 include fixABCX, fixNOQP, fixHIS, fixG, and fixLJK.
In addition, the N-terminal part of the protein possesses typical cysteine motives for coordination of two accessory [4Fe-4 S] clusters and an [2Fe2S] cluster that are involved in electron transfer from the electron donor to the active site (Vignais and Billoud 2007; Tsaousis et al. 2012).
In addition, it was identified in a unique 'Sunki Maravilha' mandarin cluster that was involved in the stress response and metabolism.
Recently, we have identified a gene cluster that is involved in lipopolysaccharide (LPS) biosynthesis in B. rhizoxinica and solved the chemical structure of the LPS [ 47].
This region spans from 27 to 54 Mb and overlaps with a previously detected quantitative trait locus and includes the inter-alpha-trypsin inhibitor gene cluster that is involved with embryo implantation.
