Sentence examples for clusters targeted from inspiring English sources

When combined with bioinformatic analysis of putative natural product gene clusters, targeted screening and isolation can be performed on a prioritized list of strains.

Of the 28,869 human transcript clusters targeted by the Human Gene ST 1.0 array our filtering method revealed 1,085 (~3.75%) transcript clusters as candidates susceptible to cross-species hybridisation (Additional file 2).

Exposure to either of the two xenobiotic ligands in this study, BaP or TCDD, causes a pronounced shift in the gene clusters targeted by the AHR, such that many of those identified in naive cells were no longer recognized by the receptor when activated by either BaP or TCDD, whereas the metabolism of xenobiotics pathway in KEGG emerged as a targeted pathway in treated cells.

Initially, clusters targeting the smallest administrative units in Ethiopia called 'Kebele' were selected using simple random sampling after obtaining the list from the district administration.

The authors showed that several miRNAs from the miR17~92 cluster targeted DNMT-1 expression resulting in a negative feedback loop [ 28].

Class 1B miRNAs miR-17-92 miR-17-92 miR-17-923 and Ezh2 with significlusterrichmentargetss of >2.

Moreover, the high similarity in genetic elements across disparate secondary metabolite biosynthetic pathways renders imprecise current gene cluster targeting strategies and contributes sequence complexity resulting in partial genome coverage.

On angiogenic VEGF stimulation, the miR-17 92 miR-17 92argets PTEN to promote endothelial proliferation.

Further work showed that miR-15a/miR-16-1 clusthe targets the anti-apoptotic BCL-2 (Cimmino et al, 2005).

Recent evidence showed that some protein complexes are enriched with single miRNA targets and some complexes are enriched with miRNA cluster targets [ 24].

We experimentally verified that the miR-141-200c clustargetsgets different components of the CtBP/ZEB complex, suggesting a potential orchestrated regulation in epithelial to mesenchymal transition.