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While certain control over the DNA surface density was possible, it was difficult to control the dispersion of DNA molecules within the film, where high density clusters of DNA molecules could be formed, in which the DNA-binding protein could hardly find its specific sequence or recognize the DNA structure.
We consistently observed two clusters of DNA FISH signals (corresponding to the two Xs).
Double-stranded DNAs are denatured and the process is repeated to generate clusters of DNA clones.
WordCluster seems to predict biological meaningful clusters of DNA words (k-mers) and genomic entities.
Widschwendter et al. reported significant differences in the HR status between clusters of DNA methylation profiles (Widschwendter et al, 2004b).
Second generation devices image a surface to which clusters of DNA grown from a template or beads have been attached.
Similar(44)
CRISPR, he learned, was a strange cluster of DNA sequences that could recognize invading viruses, deploy a special enzyme to chop them into pieces, and use the viral shards that remained to form a rudimentary immune system.
Qualitative analyses of these distributions indicated potentially increased clustering of DNA damage before the Bragg peak, enhanced γ-H2AX distribution at the peak, and provided visual evidence of high-linear energy transfer particle traversal of cells beyond the Bragg peak in agreement with one-dimensional transport approximations.
These histograms are indicative of the clustering of DNA into small tightly-packed spherical particles.
The first systematic evidence for familial clustering of DNA methylation presented longitudinal DNA methylation changes as well as genetic influences [20].
We observed the aggregation of DSBs in nuclear blebs, which indicates that MN-γ-H2AX may be derived from the clustering of DNA DSBs inside nucleus.
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