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Clusters of classes were taken from each stratum randomly.
The sample was stratified first according to the three institutions and then by colleges, and, finally, clusters of classes were randomly selected from each stratum.
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However, there are several clusters of class-specific tandem gene duplications like the cluster of three α-tubulins on chromosome 12, the cluster of two β-tubulins on chromosome 6, and the cluster of γ-tubulins on chromosome 17 (fig. 3, supplementary fig. S7, Supplementary Material online).
The two lists of differential genes had an intersection of 104 genes that separated five gene clusters from the hierarchical clustering of classes shared by the two datasets (Figure 3 and Table 5).
To increase the usability of the ontology, the Ontologizer API was used to merge all clusters of equivalent classes together into a single class.
(B ) Dendrogram showing clustering of class averages from (A ).
Ward's clustering of class profiles confirms that SOM arranged day types so that similar types are neighbors.
A similar survey in zebrafish found that, although there is a cluster of Class III genes on chromosome 19, Class III loci are spread across all chromosomes [ 8].
Contigs 7, 8 and 9 contain a cluster of class II genes belonging to the DAB gene family interspersed with DAB pseudogene fragments.
This clustering of class Ia loci by species is probably in good part explained by gene duplication and contraction, as proposed in the birth and death model [ 18].
Our study found that PML is required for normal expression of a cluster of class I MHC HLAs, including HLA-A, HLA-B, HLA-C, HLA-F, and HLA-G as PML knockdown significantly reduced the expression of these genes.
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