However, there are several clusters of class-specific tandem gene duplications like the cluster of three α-tubulins on chromosome 12, the cluster of two β-tubulins on chromosome 6, and the cluster of γ-tubulins on chromosome 17 (fig. 3, supplementary fig. S7, Supplementary Material online).
Clusters of classes were taken from each stratum randomly.
The sample was stratified first according to the three institutions and then by colleges, and, finally, clusters of classes were randomly selected from each stratum.
(B ) Dendrogram showing clustering of class averages from (A ).
Ward's clustering of class profiles confirms that SOM arranged day types so that similar types are neighbors.
A similar survey in zebrafish found that, although there is a cluster of Class III genes on chromosome 19, Class III loci are spread across all chromosomes [ 8].
Contigs 7, 8 and 9 contain a cluster of class II genes belonging to the DAB gene family interspersed with DAB pseudogene fragments.
This clustering of class Ia loci by species is probably in good part explained by gene duplication and contraction, as proposed in the birth and death model [ 18].
Our study found that PML is required for normal expression of a cluster of class I MHC HLAs, including HLA-A, HLA-B, HLA-C, HLA-F, and HLA-G as PML knockdown significantly reduced the expression of these genes.
Phylogenetic analyses highlight the clustering of Class IIB loci by species rather than by orthology relationships, suggesting a history of concerted evolution, at least on portions of the genes [ 38, 60, 61].
Additional clustering of class I MHC and ICAM-1 by a cognate interaction between antigen-laden DC and antigen-specific CD8+ T-cells induces formation of transferrin-positive tubules emanating from the endosomal recycling compartment (ERC).
