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Bundles are clusters of channels that media companies like Disney sell to cable, satellite and telephone companies.
At the level of the cell, one is often interested in the temporal evolution of gating variables describing the activity of channels (or clusters of channels), as well as the evolution of membrane voltage at the cell body and along axons and dendrites.
Gap junctions are clusters of channels that join two cells together and consist of building blocks of two connexons or hemichannels, one contributed by each of the communicating cells.
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However, few studies have documented a continuum of fluvial-depositional architectures along km-scale transects where clusters of channel bodies can be observed in their entirety.
We propose that activity-dependent regulation of TRPV1 mobility could, like for Orai, lead to clustering of channels in regions of the cell where they are most needed.
Furthermore, regions of concentration of SERCA pumps often coincided with clusters of CaV2 channels, but not CaV1 channels.
As an example, 38.3% of all the BK channels are located in clusters of 6 channels or more, whereas a binomial distribution would give a figure of 8.3% (significantly different, P<0.005).
S-MAC results in clustering of channel activity and is hence vulnerable to a statistical jammer.
The MAGUK family of proteins has been extensively studied in recent years and shown to play a role in the formation of cell junctions, maintenance of cell shape, [ 3- 5] and clustering of channel proteins at the cell surface [ 6- 8].
The sciatic nerves of these mice often showed binary clusters of Nav channels, heminodes (see Figure 3E), and Kv channels aberrantly moved into the paranodal axon membrane in association with improperly formed paranodes (Devaux and Scherer, 2005).
Our results also showed that it is highly likely that the overexpression of flotillin-1 increased the formation of nonconducting clusters of Kv2.1 channels, resulting in the decrease of Kv2.1 current amplitude.
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