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It is clear now why the array is the most homogeneous (optimal) at T gr = 360°C and h Ge = 10 Å, whereas the dispersion of the cluster sizes is increased at higher and lower values of h Ge because of the small clusters contained in the array.
The number of orthologous clusters contained in each individual genome ranged from 3451 to 5211 (Table 1).
For a less difficult dataset, we ran the algorithm on all clusters contained in more than one input tree.
Namely, these proteins are shown to be dedicated specificity factors for assembly of the Fe-S clusters contained in Rli1, a protein essential for ribosome function in yeast.
To evaluate the running time on an extremely hard dataset, we ran our algorithm on the set of all 1334 clusters contained in the nine trees.
The maturation of proteins that contain Fe-S clusters is complicated, probably because free forms of both iron and sulfur are toxic, and Fe-S clusters contained in many proteins are highly sensitive to oxygen.
Similar(52)
Clusters containing in-paralogs were subjected to monophyly masking, that is, all but one representative paralog per taxon were removed from the alignment.
This generated 23,724 clusters containing in total 282,061 sequences, while 66,934 sequences were singletons.
**) Six out of 20 clusters contain in fact largely identical Genomic Islands, which explains their high compositional similarity.
The Development Model for Integrated care (DMIC) describes nine clusters containing in total 89 elements that contribute to the integration of care.
By using maximum intervals of 500 kb, we detected a total of 53 cis-eQTL clusters (containing in average 4.9 ± 3.5 cis-eQTL genes, ranging from 3 to 19, within intervals averaging 467 ± 486 kb), and 59 control clusters (containing in average 5.2 ± 2.5 detected genes, ranging from 3 to 17, within intervals averaging 456 ± 119 kb).
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