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These authors did not elucidate the causes of this clustering of increased mortality but suggested that environmental pollution, occupational exposures and social factors could be involved.
The major histocompatibility complex (MHC) locus on chromosome 6 was shown to have local clustering of increased gene expression across a large chromosomal area spanning nearly 4 Mb [ 28].
For our nine target genes, significant clustering of increased expression was noted within the MAGEA family of genes.
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Starting around 4200 cal BP, eight distinct clusters of increased cumulated probability density functions of the 14C dates were observed, representing enhanced alluvial deposition and/or fluvial activity.
A maximum of 50% was used because once the scanning window covers more than half the geographic region and/or time period, the likelihood no longer reflects a cluster of increased risk inside the scanning window (Kulldorff et al. [1998]).
One cluster of increased FA, in the right supramarginal gyrus region, was also detected.
Cerebrospinal fluid (CSF) analyses detected clusters of increased volume in the 22q11.2DS group that co-localized with many medial GM reductions and indicated lateral and fourth ventricle dilation.
Clusters of increased brain activation for twins scoring high on obsessive compulsive symptoms were noted in the right parietal cortex (Clusters F and G) and left cingulate cortex (Cluster H).
Clusters of increased BOLD activation as a function of TOT were found in TBI survivors, as compared with healthy controls, with main peaks in the IPL and PFC in the right hemisphere.
There was a strong decline in mortality, and two highly significant clusters of increased mortality were found for the first 5 years, 1998 2002, in the south-east and in the north of the study area.
The results showed that in MDD patients the cluster size of reduced glucose metabolism was higher than the cluster size of increased glucose metabolism.
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