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Interrupted time series analyses, Bayesian analysis and ARIMA may be suited for adjusting for clustering of effects within sites, while accounting for patient-level effects, and site-level structural measures.
Both models also incorporate adjustments for intragroup correlation caused by the clustering of effects among persons infected with the same parasite strain.
However we anticipated that group processes may lead to a greater clustering of effects and decided to use an ICC of 0.175 for this trial.
The analysis of pain reduction against baseline fracture age exhibited a clear clustering of effects, with clinically significant pain reduction prior to 60 days and much less pain reduction between 60 and 120 days.
Thus, in at least three instances (A, R and Np) it is not necessary to postulate a closely linked set of genes that form a co-adapted complex in order to explain this clustering of effects on the linkage map.
However, identification and evaluation of multiple, small additive effects on clinical outcome following chemotherapy will require robust and novel statistical and computational approaches that allow nonrandom clustering of effects to be identified.
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In trials of complex interventions there is likely to be clustering of the intervention effect within therapists.
We used a mixed-effects linear regression model to assess the effect of the MESH-QI intervention on the danger sign assessment score, controlling for potential confounders and the clustering of effect at the health center level.
Multilevel modelling will be used to allow for clustering of effect within a site and Family Nurse.
Sometimes it may refer to clustering of effect modifiers within a distinct diagnostic group, what may be referred to as a 'clinical sub-group'.
All analyses accounted for the random effects of clustering of patients within providers.
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