HR inspired the clustered heatmap presentation.
Clustering in presentation does not necessarily represent evidence of separate mechanisms.
After the run of major fashion weeks in New York, London, Milan and Paris, L.A.'s twice-yearly slate of runway shows and presentations — loosely clustered around the market-week calendar — tends to suffer by comparison.
However, at the individual level, the clinical presentations are clustered, distinctly recognizable, and often strongly familial, suggesting a restricted number of archetypal disturbances, possibly involving a small number of genetic origins, neurotransmitters, and brain circuits.
Heatmap presentation, clustering analysis and PCA suggested a high reproducibility of the response across different cell preparations.
They hypothesized that a trigeminovascular and parasympathetic pathways activation, secondary to hypothalamic dysfunction related to hypothalamic pituitary axis alteration, or a vascular nociceptive receptor activation, secondary to cavernous sinus and tributary venous outflow obstruction, could explain the cluster-like presentation of IIH.
The complex, cluster-like presentation of MDD became evident through subjects' descriptions of symptoms as impacts and vice versa (e.g., decreased concentration as a symptom and/or impact of MDD).
We performed 50 runs of K-means clustering with K set to 4, 5, or 6, using Euclidean distance, and we selected the grouping into 5 clusters for presentation, as it yielded a clear separation into well-defined classes of comparable size.
Viruses in the AlphaPVs genus (encompassing viruses with different clinical presentations, namely GenW, CutW, and MucL) clustered together only for the E7 and E4 genes, but grouped separately for other genes, according to their clinical presentation (fig. 5).
Various tools are included to facilitate this objective, e.g. advanced structure search, clustering, cataloguing and tree presentation of cognate ligand receptor pairs.
