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Little is known about molecular determinants underlying physiologically important cluster organization of Cav1.2 channels in neurons [52].
Cluster organization of co-expressed genes was also found to be true for human chromosomes [40], [59], [60], though these do not have noticeable regions where genes prefer to be located on one strand.
Also, another control would be necessary to address to what extent the observed association is influenced by the cluster organization of miRNAs.
Figure 4A represents the k-means cluster organization of the RSC and ISW1a occupancy based on the microarray data, and was provided entirely for illustrative purposes to simply show the similarity of RSC and ISW1a occupancy.
An interesting finding in this context is the detection of snoRNAs (TB2Cs1C1, TB10Cs6C1 and TB9Cs7H1) that are present in the genome as singletons, and are not part of the usual cluster organization of snoRNA in trypanosomatids.
Both species possess a single pgip locus, with a cluster organization of the paralogs, and regions flanking the pgip array that maintain the strongly conserved distribution of the genes observed in the soybean and bean.
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In actuality, these two figure panels represent independent k-means cluster organizations of different data.
Clustered organization of nodes with aggregation of data at the cluster head becomes one of the significant means to extend life expectancy of the network.
However, the clustering organization of these miRNAs is not conserved in Aedes.
A simple measure of syntactic similarity does not reveal the underlying clustered organization of the code.
Such clustered organization of α-defensin genes is common in other species, suggesting that α-defensin have arisen from a common ancestor by gene duplication followed by diversification [ 3].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com