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This gene cluster organization is well conserved in species producing a T2SS apparatus.
This gene cluster organization is seen in type 1 fimbriae (fim), S fimbriae (sfa), F1C fimbriae (foc) and the Dr-antigen recognizing fimbriae (dra) [10].
This cluster organization is conserved in Xenopus, mouse, and human [ 12, 13].
This cluster organization is remarkably similar to the intact chordate ParaHox clusters found in amphioxus, Xenopus, mouse, and human [ 13].
Interestingly, a DOF cluster organization is present in the promoter of the grape VvMYB60 gene, a putative ortholog of AtMYB60, indicating a conservation of the cluster structure during the evolution among AtMYB60 orthologs [ 32].
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Genetic abnormalities in rRNA gene cluster organization are associated with increased rRNA methylation during cellular senescence [45].
In order to check whether such PtSIT2 cluster organization was not due to genome sequence misassembly we performed different amplifications by PCR using genomic DNA (Supplementary Fig. S1).
Interestingly, the most distant lipid clusters 1 and 10 were positively correlated, which suggested that this hierarchical view on cluster organization was a suboptimal representation of lipid coregulation.
UNICEF, through its partners, Ramakrishna Mission Lokshiksha Parishad and 12 cluster organizations, is moving in pre-positioned emergency supplies that include 2,000 water jerry cans, 800,000 water purification tablets, 3,134 family hygiene kits and 90,000 packets of oral rehydration salt.
One third of Anopheles miRNAs are closely linked in the genome, and such clustering organization is largely conserved between Aedes and Anopheles.
All these SERPINA3 cluster organizations are analogous to the one observed at the family level, that is for SERPINA.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com