Microscopic clusters of tissue debris were flung off the valve's shaggy edges into the student's bloodstream and carried throughout his body.
However, unsupervised classification or clustering of tissue samples should also be studied since in many cases, labeled tissue samples are not available.
Similarly, the tight clustering of tissue types having related biological functions is striking.
Clusters of tissue specific genes can be distinguished for root, seed, pod, flower, aerial tissues (l/p/s/b), root tissues (r/n/m), nodule and mycorrhiza.
The entire dataset shows clustering of tissue samples regardless of the developmental stage suggesting early completion of the transcriptional programs in the minipig (Fig. 4a).
Two clusters of tissue samples emerged at the lowest level of association: one cluster of 14 tumors designated cluster "E" and a second cluster including the remaining tumor 27 samples, as well as the four normal cerebellar controls.
Logarithmic transformation again serves to improve the clustering of tissue types to some extent, but there is still systematic variation in the raw data that remains problematic even after removal of potential bias from differences between bioinformatics pipelines.
Hierarchical clustering of tissue culture and xenograft samples demonstrated that for each individual tumor line, the in vivo and in vitro profiles were more similar to each other than any other profile.
While tissues with similar functions, such as muscle (skeletal muscle and heart) and immune tissues (lymph node and spleen) did not cluster together when assessing CpG methylation, the immune tissues did cluster together when assessing non-CpG methylation, highlighting the differential clustering of tissue types when assessing CpG and non-CpG methylation.
Statistical analyses identified genes differentially expressed among tissues and clusters of tissue-enriched genes.
This suggests that considerable clusters of tissue-specific genes do exist in higher eukaryotes.
