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As a result, most numerical ratings are clumped near the very top, with a smaller cluster of negative ratings near the bottom.
The first peptide (GADD45 β69–86) was designed by considering only the sequence of the α-helix (residues 69 86) and avoiding the cluster of negative residues.
The data points were distant enough from the cluster of negative data that produced statistically significant linear relationships between individual FAEE concentrations and drinks/week, drinking days/week and, in a lesser extent, drinks/occasion.
There was very little recognition of depression either as a medical diagnosis or as a cluster of negative emotional symptoms, even when informants themselves had faced significant social and emotional difficulties.
But then the question would be why this cluster of negative features comes to be associated together, and why is there this residual association with 'malingering', after 100 years of psychiatric orthodoxy saying otherwise?
They analyzed the contribution of these tyr residues and conclude that the phosphorylation of Y754 of the E-cadherin is the only tyrosine significantly involved in the binding, and also that a cluster of negative charges from acidic amino acids around this Y754 of E-cadherin was also important.
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Limiting the simultaneous clustering of negative equity mortgages could reproduce the structural advantages of the amortization era, when inevitable downturns disparately impacted homeowners with different levels of equity and could more easily be absorbed by the market.
A similar order results from the number and clustering of negative charges lining the non-prime subsites, explaining the gradually decreasing requirement for basic residues N-terminal to substrate cleavage sites.
The distributions among the five and three classes (as mentioned by clustering of negative and positive values, each) individually per dimension shown in Figure 6 further illustrates the reason to be found in choosing the three over the five classes in the ongoing.
They also possess clusters of negative charges on the surface [ 12- 14].
Clustering of negative vaccination statuses or sentiments about vaccination leads to clusters of unprotected individuals that increase the likelihood of disease outbreaks [ 21].
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