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It is possible, for instance, that the pattern of repeat visits might change during a cluster of illness.
However, if an outbreak or cluster of illness is too small, the method used currently for syndromic surveillance cannot trigger a statistical alert.
Reportable findings can include individual findings (e.g., a disease carrier state) or population findings (e.g., an outbreak or cluster of illness).
Early detection of SARS cannot simply focus on emergency room or outpatient encounters, since nosocomial infection may be the first indication of a cluster of illness.
Although most listeriosis cases are sporadic (i.e., not associated with a recognized cluster of illness), the detection of a listeriosis outbreak is a critical opportunity to prevent additional illness and death by removing a contaminated vehicle from the food supply.
An unexpected temporal or geographic cluster of illness of apparently infectious nature or an unusual age distribution of pneumonia with respiratory failure, intradermal hemorrhage, or chickenpox-like illnesses may indicate infection caused by a novel agent or a bioterrorist act.
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Dr. Janet Woodcock, director of the Food and Drug Administration's drug center, said that German regulators uncovered a cluster of illnesses among dialysis patients who took contaminated heparin.
"We have strengthened our surveillance system in order to give us any early warning signs of an illness or a cluster of illnesses that would suggest exposure to a bioterrorist agent," Dr. Cohen said in a telephone interview.
She said the Hillandale recall was prompted when Minnesota officials traced a cluster of illnesses in that state to the eggs from the company's Iowa plants.
Gulf War syndrome, cluster of illnesses in veterans of the Persian Gulf War (1990 91) characterized not by any definable medical condition or diagnostic test but by variable and nonspecific symptoms such as fatigue, anxiety, muscle and joint pains, headaches, memory loss, and posttraumatic stress reactions.
A recent cluster of illnesses in southern France was associated with ingestion of figatelli, a pig liver sausage mainly eaten raw (3 ).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com