Although GPS did not demonstrate geographic clustering, lack of clustering is not unexpected because the camp was small and its population density was high, making social networks, rather than absolute physical distance between dwellings, the most important facilitator of TB transmission.
Some of the isolates of this cluster lack the Avrblb1/ipiO class I gene and were found to be virulent on potato plants carrying the Rpi-blb1 resistance gene.
Conversely, conservation of an amino acid in one cluster and lack of conservation in a sister cluster is assumed to contribute to functional differences between the paralogs.
A total of 2702 probes (1787 unique genes) showed decreased expression in the inflammatory SSc cluster and lack of coherent functional enrichment (Fig. 3, brown gene cluster).
For example, nausea, constipation and vomiting accounted for 90% of the variance in the GI/pain/cognitive function symptom cluster, while lack of appetite explained only 0.8% of the variance (Table 6).
With respect to the salmonid lineage, we propose that Atlantic salmon lost Cluster 2 prior to the salmonid-specific WGD, which duplicated Cluster 1, thus producing the two copies of Cluster 1 and lack of Cluster 2 seen within the Atlantic salmon genome today.
Soon after its discovery, the ectopic expression of a truncated version of the cluster (lacking miR-92) in B-cell lymphoma revealed its oncogenic character and miR-17/92 miR-17/92 the distinction of being the first 'oncomir'.
In cluster-RCTs, lack of concealment of allocation is not considered a major risk of bias since all clusters are usually randomized at the same time (Higgins 2011, Section 16.3.2).
The large number of proposals to adjust MH for clustering suggests lack of resolution of the issue [ 18, 19].
However, the utility of this pioneering approach was limited by the greedy nature of clustering and lack of a quantitative measure of interactions between genes.
