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Primer sets for quantifying the expression of the ustiloxin B cluster genes are listed in Additional file 1: Table S1.
The interferon cluster genes are found deregulated in virus induced pathologies such as papilloma virus induced cervical cancer, and viral hepatitis.
Within the three BoNT/A1 strains, the nucleotide sequences of the toxin cluster genes are identical for the 11.7 kb region that encodes HA70, HA17, HA33, BotR, NTNH, BoNT and their intergenic regions.
In mammals, the protocadherin cluster genes are organized into three closely-related subclusters, namely the α, β and γ subclusters, each of which contains 15 to 22 homologous "variable" exons that are arranged in tandem [2].
These two very different arrangements of the toxin cluster genes are highly conserved even though they exist in very different genomic backgrounds, and illustrates the functional role each of these genes must have in the expression, protection or transport of the neurotoxin.
Results show that two zinc cluster genes are essential.
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While inside a cluster, genes were highly related, proteins encoded by the two different clusters were more divergent [3], [9].
Immune response cluster genes were reported as differentially regulated in inflammatory conditions such as ulcerative colitis, Crohn's disease, and Helicobacter pylori infections.
Despite the advances in understanding the oncogenic contributions of the menin-MLL complex, precisely how expression of Hoxa cluster genes is regulated in hematopoietic cells remains unclear.
Within each phase cluster, genes were ordered using hierarchical clustering implemented in R for display purposes.
Orthologous CCA cluster genes were not detected in the genomes of these two species.
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