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In the genomes of WCS417 and WCS374, ORFs encoding structural and regulatory components of the T3SS are organized in 26-kb and 18-kb clusters, respectively, and several ORFs within each cluster display a significant degree of similarity to the hrp/hrc cluster of pathogenic bacteria.
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This cluster displays a dense network of FIC trainees and, typically, multiple collaborations.
A few genes downstream, SCO0382 and SCO0383, which are categorized as secondary metabolism genes (deoxysugar synthase cluster) displayed a similar pattern.
For instance, the ZEB2 cluster displays a classical winner-takes-all pattern in all species except zebrafish, where we observe reciprocal retention.
Classification of a spike cluster as representing a 'single unit' required that the cluster displayed a distinct spike shape and was fully separated from both the origin (noise) and other clusters (multi-unit) with respect to at least one principal component projection.
Using spatially-resolved spectroscopy of discrete regions, hardness ratio and temperature maps, we show that all three clusters display a complex temperature structure.
The double-integrated simulated spectra for the single iron-sulfur clusters display a ratio of 1∶1 indicating the presence of both clusters FeSI and FeSII in the same amount in the protein.
To assess which cell lines in those clusters display a significantly synergistic or antagonistic response to combined EGFR-PI3K inhibition, we employed a rank sum-based statistical test (Fig. 3A).
To verify that RAG1/2 cleavage activity is primarily dependant on RSS accessibility, we used DNA from TCRβ enhancer-deleted (Eβ−/−) thymocytes in which Dβ-Jβ clusters display a heterochromatin structure [10], [28].
Due to the lack of number of cities, the confidence intervals from other clusters display a degree of overlaps.
All metabolites in the inter-class specific clusters display a pair distance of at least 7 in the reaction network.
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