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The important clue was obtained from our study focusing on the role of p62 in Parkin-mediated mitochondrial degradation.
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Clues were obtained from the pH- and temperature-dependent UV-spectra behavior of orotamide derivatives.
A clue for identifying such kinases was obtained by using a set of kinase deletion mutants [36].
Arthroscopy is needed to make a definitive diagnosis, although useful clues may be obtained from the history and physical exam as well as from imaging studies.
Such clues can be obtained by sensitivity analysis (varying boundary conditions and parameters) and by forward modeling of the system's temporal evolution.
Rather than interrogate specific proteins for their capacity to interact with ICP0, we chose to use live-cell imaging to determine if new clues might be obtained by tracking the distribution of a green fluorescent protein (GFP -tagged form of ICP0 in HSV-infected cells over time.
Patients are often reluctant to admit to nonadherence, 125 and clues can be obtained from observing medication organization, pill counts, and refill history.
Albeit the exact mechanism that exosomes do not induce apoptosis or necrosis is yet to be determined, some clues can be obtained in the results of our current study.
In a sharp contrast to the FtsZl1 genes, genes encoding FtsZl2 family proteins are not associated with any other genes, so no functional clues could be obtained as to their likely functions.
Although nothing is known in this respect, some clues can be obtained from studies of familial AD (FAD) cases that, perhaps not surprisingly, also display cell cycle abnormalities [ 54- 56].
The mechanism(s) by which probiotics interact with the host remains to be completely understood, although some clues have been obtained from studies performed using different animal models [ 11– 13].
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