If the number is prefixed with ->, as in line 16 in Figure 2B, this indicates that the bond closes a ring and points back to an atom that appeared in the output earlier.
More difficult is choosing our "molecule" for 2-D and 3-D polymers, a possibility is to include in our representation the minimum set of monomers that close a ring of the polymer, even if this may leave out important features of polymer topology, specially in the 3-D case, and not being clear if every unique atom will have a complete coordination environment.
This reaction probably takes place by nucleophilic opening of the cyclopropane ring of intermediate 54 by the carbonyl group to form an oxonium cation 55, which gives 56 by a Prins-type intramolecular reaction closing a seven-membered ring.
Male solidarity is pushed to its furthest point: the courtiers scrum around the Duke to hide his love crimes, closing in a ring around him and punching the air at the crucial moment like spectators at a cock fight.
The task force discovered several recently evacuated en emy base areas but no signifi cant numbers of troops as the allies began to close a giant ring around the suspected loca tion of the Communist military headquarters for operations in South Vietnam.
The other site was close to the A ring of dexamethasone.
The old feeling blazes through: [A]s we are about to part, having paid our bill, the circle in our blood, broken so often, so sharply, for we are so different, closes in a ring.
Even more surprising is the fact that this polymer closes into a ring.
If the sequence is closed to a ring before the autocorrelation is calculated, which is more appealing from the point of view of convolution theorem, then the autocorrelation would not fade for larger periods and the deflation effect of Hybrid estimate would be much smaller (if any).
In 1966 Kornberg and Goulian discovered an enzyme called ligase that closes a DNA strand into a ring, a configuration that makes viral DNA infectious.
