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While there are many clinical scales for assessing proprioception, they all have insufficient psychometric properties and cannot be used in closed-loop treatment paradigms wherein treatment parameters should be monitored and adjusted online or with a trial-by-trial frequency.
Image-guided adaptive radiation therapy (IGART) is a closed-loop treatment process that is designed to include the individual treatment information, such as patient-specific anatomic variation and delivered dose assessed during the therapy course in treatment evaluation and planning optimization.
Nurse intervention is not required during closed-loop treatment, apart from calibrating a subcutaneous glucose monitor.
Closed-loop treatment was superior to a local sliding-scale treatment protocol.
Automated administration of dextrose augmented the ability of closed-loop treatment to avoid low glucose levels.
During closed-loop treatment in subjects with type 1 diabetes, high-gain pulses of glucagon decreased the frequency of hypoglycemia.
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The presented platform can be applied in both the brain-machine interface and the robotic control projects, and the proposed modular hardware framework can be extended to the real-time closed-loop treatments of other dyskinesia diseases.
At ∼1600 h of the third day of monitoring, participants were admitted to the CRC and underwent randomly 24 h of open-loop treatment or closed-loop control.
Intubation timing should be adjusted based on explicit consideration of each patient situation, their fitness, the cadence and trajectory of their respiratory failure, the team's proficiency in providing noninvasive and invasive ventilator support, and emphasis on clear, frequent closed-loop communication of the treatment plan and rationale within the entire critical care team.
Borromeo was less optimistic, adding: "The only closed-loop I see here is closed-loop consumerism".
Closed-loop devices delivering medical treatments in an automatic fashion clearly require a thorough preliminary phase according to which the proposed control law is tested and validated as realistically as possible, before arranging in vivo experiments in a clinical setting.
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CEO of Professional Science Editing for Scientists @ prosciediting.com