According to our data regarding the effect of timing of insulin administration, an argument can be made for mealtime announcement by patients wearing future closed-loop devices, should these devices use current rapid-acting insulin analogs administered via CSII.
This could, therefore be used as the basis of the design of a closed-loop drug delivery device for therapeutic agents used for the management of diabetes mellitus.
The closed-loop PHIL of the device and the hardware provides insight of both the performance of the control scheme and its effect on the connected hardware.
Borromeo was less optimistic, adding: "The only closed-loop I see here is closed-loop consumerism".
In this case, the V-model will make it possible to set up a self-correcting control strategy consisting of a closed-loop control approach, measurement devices and actuators.
Whether closed-loop seizure-prediction and treatment devices will have the profound clinical effect of their cardiological predecessors will depend on our ability to perfect these techniques.
A comparison is made of a magnetorheological damper (MRD) and a friction damper (FD) in semi-active suspension design; both devices are closed-loop controlled.
