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Microscopic view in bright-field microscopy of cross sections of a recently closed wound.
The TFK-1 cells transfected with the miR-200b/c mimics also slowly closed wound gaps compared with the control.
The closed wound group of patients showed significantly shortest wound healing time, followed by the limited excision group of patients; the wide excision group of patients showed the longest healing time.
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Additionally, wound-healing assays showed that SGC-7901-FOXO4 closedclosed wounds more slowly than SGC-7901-NC SGC-7901-NC SGC-7901-NC
The most important distinction is between open and closed wounds.
It is unclear whether these results can be extrapolated to pin sites as these are not closed wounds.
The sponsor evaluated adults with chronic wounds and did not investigate the subgroup of open and closed wounds.
In such a wound-migration assay, human WT-PMP22 expressing MDCK cells closed wounds approximately 60% slower than controls and displayed reduced lamellipodial protrusions (Roux et al., 2005).
The most common method of closing wounds is by sutures.
Purdue guard Carson Cunningham needed four stitches and Wisconsin guard Mike Kelley required three stitches to close wounds from a head-on collision.
However, controversy exists over when or if to close wounds that are delayed in presentation to the ED.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com