Sentence examples for closed trigger from inspiring English sources

Because it appears that the trigger loop must be closed for rapid catalysis with a cognate substrate NTP, simulations should first be done with fully closed trigger loop conformations.

A working model for transcriptional fidelity would account for dNMP NTP alignment, hydration/dehydration, ribose/deoxyribose sugar discrimination, trigger loop opening and closing mechanisms, and clashes of the closed trigger loop with a noncognate base pair.

Because the secondary pore appears to close in a TEC with a closed trigger loop conformation and because trigger loop opening appears important for PPi release and translocation, if NTP-Mg2+ loading occurs prior to PPi release, it appears that this NTP must load through the main RNAP channel and not the secondary pore.

In agreement with crystallographic studies, the results suggest that catalysis requires a closed trigger loop and that translocation requires an open trigger loop.

So far, it appears that water must be highly ordered and in some places specifically excluded in a closed trigger loop RNAP TEC.

Coupled with PPi release, the closed trigger loop is partially opened, suggesting that PPi release may be stimulated by opening of the trigger loop.

The shortfall will force some smaller nonprofit home healthcare agencies to close, trigger layoffs at others and leave thousands of elderly people scrambling for alternatives to in-home care, said Bob Thieman, executive director of the Illinois Association of Community Care Program Healthcare Providers.

Announced by the People's Bank of China in a terse statement published on its Web site after the Chinese stock market had closed, it triggered selling in riskier assets like the euro and oil.

Once the paper spray sample cartridge was placed on the tray and inserted into the system, a magnetic switch closed and triggered the analysis.

It appears that closing the trigger loop closes the pore.

Unlike most modern pump-action shotguns, the Winchester Model 1897 (versions of which were type classified as the Model 97 or M97 for short) fired each time the action closed with the trigger depressed (that is, it lacks a trigger disconnector and is capable of slamfire).