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When the library is closed, the study spaces are accessed from a "24/7" door outside the library.
Of note 9/24 patients (38%) who experienced a first CVE were dead when we closed the study in 2007.
An early stopping rule would have closed the study after 14 patients if no RECIST responses had been seen as this would indicate a 95% probability of the true response rate being <20%.
This estimate assumes that the probability of being captured by 1 system does not affect the probability of being captured by the other, that the population is closed (the study population remained approximately constant and without significant migration during the study period), and that the ascertainment of influenza by the surveillance systems is valid (21 – 21 ).
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Plenty of great shots: I loved Betty closing the study door before we cut straight to Suzanne opening the front door to let Don in.
Results and conclusions close the study.
It was decided by the sponsor to close the study to accrual prematurely on 31 December 2010.
Closing the study due to futility may only decrease the type I error rate.
The steering committee is allowed to close the study ahead of schedule.
Close-out visits are conducted to close the study site at the end of the study and to ensure that all study-related documents archived.
After the feasibility study had been opened for a period of 18 months, a decision was made to close the study on the basis of failure to recruit.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com