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Rather than forming a closed ring, the Rho hexamer is split open, resembling a "lock washer" in its global architecture.
The closed ring of the molecule is similar to the hemoglobin of our blood, but holds a magnesium ion rather than iron.
A biochemical study reveals the AAA+ protein unfoldase ClpX functions as a closed ring and identifies regions required for intersubunit coupling during the ATPase cycle.
The overall structure of the closed ring in the presence of ATPγS was similar to that observed in cryo-EM images of ClpB reported recently18.
The center value of the circularity distribution for the closed ring under the ADP condition was slightly lower than that measured under the ATPγS condition (Supplementary Figure 7b).
Structural instability of the distorted closed ring possibly accelerates the ATPase cycle of Y494D mutant, resulting in a high ATP hydrolysis activity (~8 s−1).
Similar(20)
Planar ring structure has five transition metal atoms and five sulphur atoms which form a closed ring-like loop.
The aromatic series is an unsaturated closed-ring series.
The lower and higher circularity peaks correspond to the open- and closed-ring states, respectively.
The naphthenic series has the general formula CnH2n and is a saturated closed-ring series.
The naphthene series has the general formula CnH2n and is a saturated closed-ring series.
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