Your English writing platform
Discover LudwigExact(3)
"When I took over it was a closed organization," he says.
Many Catholics have felt for a long time that the church is a closed organization run by a select group committed to secrecy, which has often done great harm to the church.
In human, the nucleosome landscape at the promoter region has a bimodal distribution, with a relatively open organization for expressed genes and a relatively closed organization for silent genes (Additional file 1: Figure S12).
Similar(55)
Software ecosystems is an emerging trend within the software industry, implying a shift from closed organizations and processes towards open structures, where actors external to the software development organization are becoming increasingly involved in development.
Marie Stopes Kenya is a nongovernmental organization, however, and a "closed system" delivering family planning via fixed sites and mobile services (in private-public partnership with the Ministry of Health).
Their closed nucleosome organization encoded in DNA seems to protect these cryptic sites.
We speculated that the DNA-encoded closed nucleosome organization protects unbound motifs at vitro+/vivo+ promoters.
Other factors override the underlying DNA sequence to form the closed nucleosome organization at vitro-/vivo+ promoters.
In addition, they employ nucleosome sliding rather than nucleosome eviction to retain the closed nucleosome organization and regulate access to DNA.
Although vitro+/vivo+ promoters have similar closed nucleosome organization both in vivo and in vitro, they are shown to be highly regulated by chromatin remodelers (P < 10-5, Mann-Whitney U-test).
Insights into the four modes of nucleosomal regulation reveal that DNA encodes closed nucleosome organization to occlude cryptic sites between some divergent gene pairs, and high intrinsic TF-DNA binding affinity is associated with nucleosome displacement that overrides the underlying nucleosome sequence preferences.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com