General Anesthesia was maintained with propofol and muscle paralysis was maintained using a closed-loop computer controlled infusion of cisatracurium.
Perhaps more enticing is the possibility for future iterations of a closed-loop computer protocol with evidence-based, detailed rules that capture the decision-making processes of our best clinicians.
A 0.1 mg/kg initial bolus of cisatracurium was administered before tracheal intubation, followed by a closed-loop computer controlled infusion of cisatracurium to produce and maintain a 90% neuromuscular block.
The closed loop control system relied on study personnel to transmit data manually from the continuous glucose monitor to the computer running the closed loop control, and to transmit insulin injection recommendations from the computer to the insulin pump.
The testing apparatus, based on a ring test, is presented with its own computer-controlled closed loop.
This paper shows new possibility of the robust design of simple controllers based on computer analysis of closed loop transient responses achieved over predefined grid of possibly normalized loop parameters by simulation, or by measurement.
The closed loop system performance is investigated through computer simulations and is compared by those achieved from implementing two commonly used controllers i.e. PI and feedback linearization based PID.
Incorporating an accurate continuous blood glucose analyzer validated for critically ill patients and an effective, safe, and validated computer algorithm into a closed loop system can help to avoid harmful clinical errors leading to iatrogenic-induced hypoglycemia and to successful implementation of TGC.
Now, the company is transforming some of the collected plastic waste into new materials for its OptiPlex 3030 desktop computer, creating the industry's first certified "closed loop" recycling system.
