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The TIM barrels can vary from closed barrel structures to open, splayed barrels.
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Although some servers used OB-folds as templates, the significance of those predictions is unclear as the templates were closed barrels.
For OmpW proteins, the 8-stranded barrels are narrow enough so that interactions between polar/charged residues on opposite sides of the barrel wall effectively close the barrel towards the periplasm.
In his opening argument, a defense lawyer, William R. Martin, suggested that the gun might have misfired when Mr. Williams closed the barrels.
Some barrel superfamilies on which we tested have only strand pairs of interleave 1 or 2, excepting a pair of beta strands that close the barrel and thus have an interleave equivalent to the number of strands in the barrel.
A disulfide between Cys61/139 (Figure 5) could even close the barrel completely.
The first two strands are linked together by two α-helices, which close the barrel from one end.
It contains a long, water-cooled gun barrel closed at one end and open at other end.
He said the debris and a vibration caused the gun to malfunction and fire, without a trigger pull, when Mr. Williams jerked it upward to close its barrels.
Crude oil prices on the New York Mercantile Exchange hit $66 a barrel before closing at $65.80 a barrel, up 90 cents.
For example, he estimated that the recent rise in oil prices, from $75 a barrel to close to $100 a barrel, had cost the American economy about $100 billion.
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