"He'll say, 'Robert, I just saw you getting asked X.' " But Valerie Jarrett, the adviser who is personally closest with Obama, cautioned against over-interpreting his channel surfing.
The running mash emerged from a concealed rubber hose which, when traced as far as was consistent with caution, led close to petitioner's home.
Hydromorphone has been found to be safe and effective in patients with impaired renal or hepatic function, although it is advised to be used with caution and close monitoring owing to the increased exposure to (mean Cmax and AUC were 2- to 4-fold higher) and slower elimination of hydromorphone and its metabolites in these patients [ 25- 29].
Based on these findings, WHO recommends avoiding NVP in women, including pregnant women, with CD4 counts between 250 and 350 cells/mm, or if no other options exist as it is often the case in resource-limited settings, using it with caution and close monitoring during the first 12 weeks of therapy [ 2, 8].
NVP-based HAART should continue to be used with caution and close monitoring in eligible women for HAART with absolute CD4 cell count between 250 and 350 cells/mm3 and in eligible pregnant women in resource-limited settings if no other options exist.
Additional in silico analysis on simulated MIRU-VNTR genotype population datasets showed that the MIRU-VNTR pattern similarity could partly arise due to probabilistic increase of acquiring homoplasy among subpopulations, thus the similar MIRU-VNTR profiles of M. avium strains even in close geographical proximity should be interpreted with caution.
Finally, we did not adjust for multiple comparisons, and therefore P-values close to 0.05 should be interpreted with caution.
As noted above, BOC and TVR are both inhibitors of CYP3A4, and concomitant administration of medications known to be CYP3A4 substrates should be done with caution and under close clinical monitoring.
Pharmacokinetic interactions have particular implications in HIV-coinfected and transplant populations, where drug drug interactions will complicate treatment paradigms, so that any use of BOC or TVR in transplant or HIV-coinfected populations of patients with HCV should be done with caution and under close clinical monitoring.
The study results should be extrapolated with caution to settings where close monitoring cannot be offered.
Statistically significant findings close to the nominal level (α=0.05) should be viewed with caution.
