Sentence examples for close to the reference genome from inspiring English sources

RD based clustering showed that HP strains (ST1 and ST7) were grouped together and were most close to the reference genome.

The second parental strain was generated by introducing ~0.2% of SNVs to the reference genome randomly to mimic a strain that was close to the reference genome.

Interestingly, even in the two lines that are the closest to the reference genome (LA 0147 and Levovil), one half to two-thirds of the SNPs remained specific to each line.

The isolates, which shared a phage type similar to DT135 known locally as 135@ or 135a, formed a clade within the S. Typhimurium population with close similarity to the reference genome SL1334 (160 single nucleotide polymorphisms, or SNPs).

Three other M. oryzae rice isolates were recently newly sequenced (Yoshida et al. 2009; Xue et al. 2012; Wu et al. 2015), and their genome structure and composition was very close to the 70-15 reference genome.

Alternatively, in the "assemble-then-align" strategy, the reads are first de-novo assembled and the resulting contigs are then aligned to the reference genome to close gaps and create scaffolds [ 41].

The trimmed reads for each sample were aligned to the reference genome using the GSNAP aligner23.

De novo scaffolds recruitment to close gaps in the reference genome sequence was done as follows.

After sequence reads were mapped to the reference genome, mpileup files against the dog reference genome were generated using samtools48.

Some 3.5percentt of Dr. Watson's genome could not be matched to the reference genome.

The sequences that aligned to the reference genome as described above were sorted by the start position of their alignment to the reference genome.