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The increase of fitness varied among clones, with higher increases in clones with lower initial values (D1, D1.5 and D2).
Clones with lower mCrem expression all exhibited dose dependent recombination, with the clone with the lowest apparent mCrem expression (based on a qualitative assessment of the western blot in Fig. 3A), 27Flip/Cre31, showing the lowest level of activity at 1 nM Cre.
In addition, unknown molecular function was observed at a lower frequency for BBRAF clones with higher homology to Arabidopsis genes (≤1e − 150) than for BBRAF clones with lower homology to Arabidopsis genes (Fig. 2B).
Protein synthesis is an energy consuming process for all cells, and if type IV collagen synthesis was not of importance for cancer progression, clones with lower collagen production would have emerged and gained advantage in the cancer cell population.
For example, intuitive assumptions might be that patients who experience later than normal recurrence harbor more indolent resistant clones with lower fitnesses or that a smaller tumor size at recurrence signifies a less diverse relapsed tumor population.
> -wrap-foot> Results of studies by Ackermann et al [ 4] and Credito and Applebaum [ 7] showing more potent activity of fidaxomicin against C. difficile than those of Karlowsky et al [ 8], Hecht et al [ 6], and Finegold et al [ 5] may have been related to the inclusion of higher numbers of clones with lower MICs.
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In two distinct tissues in Drosophila, the ovarian follicle and the wing imaginal disc, epithelial cell clones with lowered ph function (either homozygous for the ph504 amorphic allele or expressing a transgenic RNAi construct targeting ph) are expulsed as a tight cell mass exhibiting important cell polarity and adhesion modifications.
This dependence on the dimensionality shows that the fidelity of the cloned qubits can be as high as, while states with higher dimensionalities d can only be cloned with lower fidelities down to 50% in the limit of d∞.
Supplementing mixture X (TmXyn10A xylanase and BpXyn43 β-xylosidase) to mixture C led to a significant increase (by 25to71%1%, t-test: P < 0.01) in xylose release from the pith of the H58 clone with lower lignin content, whereas the increase was less significant (t-test: 0.01 < P < 0.03 up to 48 h) in the interface fraction of H58.
Thereafter, individual colonies were isolated to select those clones with a lower number of copies of the STEMCCA provirus.
The data was quality-filtered by removing those clones with quality lower than 0.5 in more than 20% of all the samples [ 19].
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