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These rat iPS clones will provide useful research tools to study rat developmental biology and rat-based models of various human diseases such as 6OHDA-lesioned rat model of PD.
The complete sequencing of the BAC clones will provide candidate genes for the D locus.
Many foundation species both in terrestrial and aquatic habitats form new individuals by either sexual or asexual reproduction, and populations formed by one or a few different clones will provide less phenotypic variation than multi-clonal populations, whenever phenotypic traits are largely explained by genetic variation.
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Identification of genomic regions specific to the pandemic clone will provide the signature DNA sequences for discrimination of pandemic strains from others.
Furthermore, the availability of these DArT clone sequences will provide future opportunities to identify polymorphisms in candidate gene loci, or to isolate series of alleles from these loci.
In combination with a unique and versatile cloning system, these will provide the tools for genome-wide systematic functional analyses, to achieve a deeper insight into complex biological processes.
Roberds and Bishir (1997) suggest that use of 30-40 unrelated clones will generally provide security against catastrophic failure.
On top of that, the company, BoyaLife, says it will provide clones of family pets.
Subsequent drug treatment of these animals, as well as careful genetic analysis of clones before and after drug treatment, will provide insight into how clones within a heterogeneous tumor respond to and become resistant to therapy over time.
Monitoring these clones in longer follow up will provide clearer information about a possible effect of vector on clonal dynamics.
Genetic mapping, cloning and characterization of ewst1 will provide deeper insights into water stress tolerance and associated changes in rice.
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